Welcome to EpiRegioDB!

EpiRegio is a resource of Regulatory EleMents (REMs), non-coding DNA regions that are able to regulate the expression of their target genes. Identifying REMs and their associated genes is an ongoing challenge in epigenomics, as there is no method yet to get a clear readout of a REM and as the target genes can be located up to several kilobases away.
EpiRegio's data is based on the results of STITCHIT, a peak-calling free algorithm that uses chromatin accessibility signal in combination with gene expression data to identify gene-specific REMs. For more details, please have a look at our documentation.
For each REM, EpiRegio provides you with information on its associated gene, its relevance for its gene's expression and its activity in different cell types and tissues. With EpiRegio you are able to look into regions of interest, analyze the genomic locations that impact the expression of specific genes and access details about the REMs.

Get started

You have different options to get the data you want:
  • query REMs by looking up specific genes
  • look into genomic regions
  • get information about the REMs themselves
  • or for a more flexible approach make use of the Rest API
For a detailed documentation including a step-by-step guide and example user cases please visit our Read the docs page. If you have questions or comments please let us know, we'd be glad to hear them.

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